Publications

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2023
Miller RM, Millikin RJ, Rolfs Z, Shortreed MR, Smith LM.  2023.  Enhanced Proteomic Data Analysis with MetaMorpheus. Methods Mol Biol.. 2426:35-66.
Milikin RJ, Shortreed MR, Scalf M, Smith LM.  2023.  Fast, Free, and Flexible Peptide and Protein Quantification with FlashLFQ. Methods Mol Biol.. 2426:303-313.
2022
Miller R.M, Knoener R.A, Benner B.E, Frey B.L, Scalf M., Shortreed M.R, Sherer N.M, Smith L.M.  2022.  Discovery of Dehydroamino Acid Residues in the Capsid and Matrix Structural Proteins of HIV-1 br. Journal of Proteome Research. 21:993-1001.
Miller R.M, Jordan B., Mehlferber M.M, Jeffery E.D, Chatzipantsiou C., Kaur S., Millikin R.J, Dai Y.X, Tiberi S., Castaldi P.J et al..  2022.  Enhanced protein isoform characterization through long-read proteogenomics. Genome Biology. 23
Dai Y.L, Millikin R.J, Rolfs Z., Shortreed M.R, Smith L.M.  2022.  A Hybrid Spectral Library and Protein Sequence Database Search Strategy for Bottom-Up and Top-Down Proteomic Data Analysis. Journal of Proteome Research. 21:2609-2618.
Carr A.V, Frey B.L, Scalf M., Cesnik A.J, Rolfs Z., Pike K.A, Yang B., Keller M.P, Jarrard D.F, Shortreed M.R et al..  2022.  MetaNetwork Enhances Biological Insights from Quantitative Proteomics Differences by Combining Clustering and Enrichment Analyses. Journal of Proteome Research. 21:410-419.
Hansen S.R, White D.S, Scalf M., Correa I.R, Smith L.M, Hoskins A.A, Staley J.P.  2022.  Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP. eLife. 11
Miller R.M, Smith L.M.  2022.  Overview and considerations in bottom-up proteomics. Analyst.
Plubell D.L, Kall L., Webb-Robertson B.J, Bramer L.M, Ives A., Kelleher N.L, Smith L.M, Montine T.J, Wu C.C, MacCoss M.J.  2022.  Putting Humpty Dumpty Back Together Again: What Does Protein Quantification Mean in Bottom-Up Proteomics? br Journal of Proteome Research. 21:891-898.
Spiniello M., Scalf M., Casamassimi A., Abbondanza C., Smith L.M.  2022.  Towards an Ideal In Cell Hybridization-Based Strategy to Discover Protein Interactomes of Selected RNA Molecules. International Journal of Molecular Sciences. 23
2021
Weisbrod C.R, Anderson L.C, Hendrickson C.L, Schaffer L.V, Shortreed M.R, Smith L.M, Shabanowitz J., Hunt D.F.  2021.  Advanced Strategies for Proton-Transfer Reactions Coupled with Parallel Ion Parking on a 21 T FT-ICR MS for Intact Protein Analysis. Analytical Chemistry. 93:9119-9128.
Rolfs Z., Frey B.L, Shi X.D, Kawai Y., Smith L.M, Welham N.V.  2021.  An atlas of protein turnover rates in mouse tissues. Nature Communications. 12
Rolfs Z., Smith L.M.  2021.  Automated Assignment of Proteoform Classification Levels. Journal of Proteome Research. 20:4101-4105.
Shortreed M.R, Millikin R.J, Liu L., Rolfs Z., Miller R.M, Schaffer L.V, Frey B.L, Smith L.M.  2021.  Binary Classifier for Computing Posterior Error Probabilities in MetaMorpheus. Journal of Proteome Research. 20:1997-2004.
Schaffer L.V, Anderson L.C, Butcher D.S, Shortreed M.R, Miller R.M, Pavelec C., Smith L.M.  2021.  Construction of Human Proteoform Families from 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Top-Down Proteomic Data. Journal of Proteome Research. 20:317-325.
Jia W.Y, Kim S.H, Scalf M.A, Tonzi P., Millikin R.J, Guns W.M, Liu L., Mastrocola A.S, Smith L.M, Huang T.T et al..  2021.  Fused in sarcoma regulates DNA replication timing and kinetics. Journal of Biological Chemistry. 297
Knoener R., Evans E., Becker J.T, Scalf M., Benner B., Sherer N.M, Smith L.M.  2021.  Identification of host proteins differentially associated with HIV-1 RNA splice variants. eLife. 10
Rolfs Z., Smith L.M.  2021.  Internal Fragment Ions Disambiguate and Increase Identifications in Top-Down Proteomics. Journal of Proteome Research. 20:5412-5418.
Lu L., Scalf M., Shortreed M.R, Smith L.M.  2021.  Mesh Fragmentation Improves Dissociation Efficiency in Top-down Proteomics. 32:1319-1325.
Miller R.M, Ibrahim K., Smith L.M.  2021.  ProteaseGuru: A Tool for Protease Selection in Bottom-Up Proteomics. Journal of Proteome Research. 20:1936-1942.
Yau B., Naghiloo S., Diaz-Vegas A., Carr A.V, Van Gerwen J., Needham E.J, Jevon D., Chen S.Y, Hoehn K.L, Brandon A.E et al..  2021.  Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet. Iscience. 24
Cesnik A.J, Miller R.M, Ibrahim K., Lu L., Millikin R.J, Shortreed M.R, Frey B.L, Smith L.M.  2021.  Spritz: A Proteogenomic Database Engine. Journal of Proteome Research. 20:1826-1834.
2020
Rolfs Z., Millikin R.J, Smith L.M.  2020.  An Algorithm to Improve the Speed of Semi and Non-specific Enzyme Searches in Proteomics. Current Bioinformatics. 15:1065-1074.
Millikin R.J, Shortreed M.R, Scalf M., Smith L.M.  2020.  A Bayesian Null Interval Hypothesis Test Controls False Discovery Rates and Improves Sensitivity in Label-Free Quantitative Proteomics. Journal of Proteome Research. 19:1975-1981.
Schaffer L.V, Millikin R.J, Shortreed M.R, Scalf M., Smith L.M.  2020.  Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data. Journal of Proteome Research. 19:3510-3517.

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