Publications

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Smith L.M, Thomas P.M, Shortreed M.R, Schaffer L.V, Fellers R.T, LeDuc R.D, Tucholski T., Ge Y., Agar J.A, Anderson L.C et al..  2019.  A five-level classification system for proteoform identifications. Nature methods. 16(10)
Smith L.M, J. Parce W, Smith BA, McConnell HM.  1979.  Antibodies bound to lipid haptens in model membranes diffuse as rapidly as the lipids themselves. Proceedings of the National Academy of Sciences of the United States of America. 76:4177-9.
Smith L.M, Hood L.  1987.  Mapping and sequencing the human genome: how to proceed. Bio/Technology. 5:933-9.
Smith L.M.  1988.  Fluorescence-based automated DNA sequence analysis. Genet. Eng. (N. Y.). 10:91-108.
Smith L.M.  1988.  Automated synthesis and sequence analysis of biological macromolecules. Analytical Chemistry. 60:381A-382A,384A-390A.
Smith L.M.  1989.  Automated DNA sequencing and the analysis of the human genome. Genome. 31:929-37.
Smith L.M.  1989.  DNA sequence analysis: past, present, and future. American Biotechnology Laboratory. 7:10,12,14,16-18,20-5.
Smith L.M.  1991.  High-speed DNA sequencing by capillary gel electrophoresis. Nature. 349:812-813.
Smith L.M.  1993.  Automated DNA-Sequencing - a Look into the Future. Cancer Detection and Prevention. 17:283-288.
Smith L.M.  1993.  DNA electrophoresis. Current Opinion in Biotechnology. 4:37-40.
Smith L.M.  1993.  The Future of DNA-Sequencing. Science. 262:530-532.
Smith L.M, Sanders JZ, Kaiser RJ, Hughes P, Dodd C, Connell CR, Heiner C, Kent SBH, Hood LE.  1986.  Fluorescence detection in automated DNA sequence analysis. Nature. 321:674-9.
Smith L.M, Brumley, Jr. RL, Buxton EC, Giddings M, Marchbanks M, Tong X.  1996.  High-speed automated DNA sequencing in ultrathin slab gels. Methods in Enzymology. 271:219-237.
Smith L.M, Corn R.M, Condon A.E, Lagally M.G, Frutos A.G, Liu Q.H, Thiel A.J.  1998.  A surface-based approach to DNA computation. Journal of Computational Biology. 5:255-267.
Smith L.M.  1996.  Sequence from spectrometry: a realistic prospect? Nature Biotechnology. 14:1084,1087.
Shortreed M.R, Wenger C.D, Frey B.L, Sheynkman G.M, Scalf M., Keller M.P, Attie A.D, Smith L.M.  2015.  Global Identification of Protein Post-translational Modifications in a Single-Pass Database Search. Journal of Proteome Research. 14:4714-4720.
Shortreed M.R, Frey B.L, Scalf M., Knoener R.A, Cesnik A.J, Smith L.M.  2016.  Elucidating Proteoform Families from Proteoform Intact-Mass and Lysine-Count Measurements. Journal of Proteome Research. 15:1213-1221.
Shortreed M.R, Lamos S.M, Frey B.L, Phillips M.F, Patel M., Belshaw P.J, Smith L.M.  2006.  Ionizable isotopic labeling reagent for relative quantification of amine metabolites by mass spectrometry. Analytical Chemistry. 78:6398-6403.
Shortreed M.R, Millikin R.J, Liu L., Rolfs Z., Miller R.M, Schaffer L.V, Frey B.L, Smith L.M.  2021.  Binary Classifier for Computing Posterior Error Probabilities in MetaMorpheus. Journal of Proteome Research. 20:1997-2004.
Shortreed M.R, Chang S.B, Hong D.G, Phillips M., Campion B., Tulpan D.C, Andronescu M., Condon A., Hoos H.H, Smith L.M.  2005.  A thermodynamic approach to designing structure-free combinatorial DNA word sets. Nucleic Acids Research. 33:4965-4977.
Sheynkman G.M, Shortreed M.R, Frey B.L, Smith L.M.  2013.  Discovery and Mass Spectrometric Analysis of Novel Splice-junction Peptides Using RNA-Seq. Molecular & Cellular Proteomics. 12:2341-2353.
Sheynkman GM, Shortreed MR, Frey BL, Scalf M, Smith L.M.  2014.  Large-Scale Mass Spectrometric Detection of Variant Peptides Resulting from Nonsynonymous Nucleotide Differences. Journal of Proteome Research. 13:228-240.
Sheynkman G.M, Shortreed M.R, Cesnik A.J, Smith L.M.  2016.  Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation. 9:521-545.
Schaffer L.V, Shortreed M.R, Cesnik A.J, Frey B.L, Solntsev S.K, Scalf M., Smith L.M.  2018.  Expanding Proteoform Identifications in Top-Down Proteomic Analyses by Constructing Proteoform Families. Analytical Chemistry. 90:1325-1333.
Schaffer L.V, Millikin R.J, Shortreed M.R, Scalf M., Smith L.M.  2020.  Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data. Journal of Proteome Research. 19:3510-3517.

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