Publications

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Smith L.M.  2006.  Nanostructures - The manifold faces of DNA. Nature. 440:283-284.
Smith L.M, Hood L.  1987.  Mapping and sequencing the human genome: how to proceed. Bio/Technology. 5:933-9.
Smith L.M.  1993.  DNA electrophoresis. Current Opinion in Biotechnology. 4:37-40.
Smith L.M, McConnell H.M, Smith B.A, Parce J.W.  1981.  Pattern photobleaching of fluorescent lipid vesicles using polarized laser light. Biophysical Journal. 33:139-146.
Smith L.M.  2010.  Nanotechnology: Molecular robots on the move. Nature. 465:167-168.
Smith L.M.  1989.  Automated DNA sequencing and the analysis of the human genome. Genome. 31:929-37.
Smith L.M, Corn R.M, Condon A.E, Lagally M.G, Frutos A.G, Liu Q.H, Thiel A.J.  1998.  A surface-based approach to DNA computation. Journal of Computational Biology. 5:255-267.
Smith L.M, Sanders JZ, Kaiser RJ, Hughes P, Dodd C, Connell CR, Heiner C, Kent SBH, Hood LE.  1986.  Fluorescence detection in automated DNA sequence analysis. Nature. 321:674-9.
Smith L.M, Kelleher N.L, Ge Y., Down PConsortium.  2013.  Proteoform: a single term describing protein complexity. Nature Methods. 10:186-187.
Smith L.M.  1993.  Automated DNA-Sequencing - a Look into the Future. Cancer Detection and Prevention. 17:283-288.
Smith L.M.  1981.  The Lateral and Rotational Motion of Membrane Components. 8115832:168p..
Smith L.M.  1988.  Automated synthesis and sequence analysis of biological macromolecules. Analytical Chemistry. 60:381A-382A,384A-390A.
Smith L.M, Brumley, Jr. RL, Buxton EC, Giddings M, Marchbanks M, Tong X.  1996.  High-speed automated DNA sequencing in ultrathin slab gels. Methods in Enzymology. 271:219-237.
Smith L.M, Fung S, Hunkapiller MW, Hunkapiller TJ, Hood LE.  1985.  The synthesis of oligonucleotides containing an aliphatic amino group at the 5' terminus: synthesis of fluorescent DNA primers for use in DNA sequence analysis. Nucleic Acids Research. 13:2399-412.
Shortreed M.R, Frey B.L, Scalf M., Knoener R.A, Cesnik A.J, Smith L.M.  2016.  Elucidating Proteoform Families from Proteoform Intact-Mass and Lysine-Count Measurements. Journal of Proteome Research. 15:1213-1221.
Shortreed M.R, Wenger C.D, Frey B.L, Sheynkman G.M, Scalf M., Keller M.P, Attie A.D, Smith L.M.  2015.  Global Identification of Protein Post-translational Modifications in a Single-Pass Database Search. Journal of Proteome Research. 14:4714-4720.
Shortreed M.R, Lamos S.M, Frey B.L, Phillips M.F, Patel M., Belshaw P.J, Smith L.M.  2006.  Ionizable isotopic labeling reagent for relative quantification of amine metabolites by mass spectrometry. Analytical Chemistry. 78:6398-6403.
Shortreed M.R, Chang S.B, Hong D.G, Phillips M., Campion B., Tulpan D.C, Andronescu M., Condon A., Hoos H.H, Smith L.M.  2005.  A thermodynamic approach to designing structure-free combinatorial DNA word sets. Nucleic Acids Research. 33:4965-4977.
Sheynkman GM, Shortreed MR, Frey BL, Scalf M, Smith L.M.  2014.  Large-Scale Mass Spectrometric Detection of Variant Peptides Resulting from Nonsynonymous Nucleotide Differences. Journal of Proteome Research. 13:228-240.
Sheynkman G.M, Shortreed M.R, Cesnik A.J, Smith L.M.  2016.  Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation. 9:521-545.
Sheynkman G.M, Shortreed M.R, Frey B.L, Smith L.M.  2013.  Discovery and Mass Spectrometric Analysis of Novel Splice-junction Peptides Using RNA-Seq. Molecular & Cellular Proteomics. 12:2341-2353.
Schaffer L.V, Shortreed M.R, Cesnik A.J, Frey B.L, Solntsev S.K, Scalf M., Smith L.M.  2018.  Expanding Proteoform Identifications in Top-Down Proteomic Analyses by Constructing Proteoform Families. Analytical Chemistry. 90:1325-1333.
Schaffer L.V, Millikin R.J, Miller R.M, Anderson L.C, Fellers R.T, Ge Y., Kelleher N.L, LeDuc R.D, Liu X., Payne S.H et al..  2019.  Identification and Quantification of Proteoforms by Mass Spectrometry. Proteomics.
Schaffer L.V, Rensvold J.W, Shortreed M.R, Cesnik A.J, Jochem A., Scalf M., Frey B.L, Pagliarini D.J, Smith L.M.  2018.  Identification and quantification of murine mitochondrial proteoforms using an integrated top-down and intact-mass strategy. Journal of Proteome Research. 17(10):3526-3536.
Schaffer L.V, Tucholski T., Shortreed M.R, Ge Y., Smith L.M.  2019.  Intact-Mass Analysis Facilitating the Identification of Large Human Heart Proteoforms. Analytical Chemistry. 91(17)

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